How does excess weight affect cancer risk?
A number of mechanisms could be involved, such as immune system function and inflammation, levels of certain hormones — such as insulin and estrogen, factors that regulate cell growth, and through proteins that influence how the body uses certain hormones.
Does losing weight reduce the risk of developing cancer?
Perhaps. Body changes, such as a reduction in the hormones insulin, estrogens and androgens that occur as a result of weight loss may reduce cancer risk.